Technical Field of Anthranilic Acid Methyl Ester

Firstly, phthalic anhydride and ammonia water are used as raw materials to generate o-formamide benzoic acid amine through amidation reaction, then sodium hydroxide solution is added to generate o-formamide benzoic acid sodium through displacement reaction, the ammonia molecules in the reaction solution are removed, then methanol solution and sodium hypochlorite solution are added to the reaction solution to generate paste like anthranilic acid methyl ester, and the paste like anthranilic acid methyl ester is heated after dissolving with water, the mixture of anthranilic acid methyl ester and water is distilled to obtain anthranilic acid methyl ester. The content of anthranilic acid methyl ester obtained by the invention is high, up to 98.4%; the appearance is good, the light transmittance of the product is 58.6%; the yield is high, 0.4%-0.5% higher than the original process; the process technology is advanced, ammonia water and methanol can be recycled twice, and there is no "three wastes" discharged in the production process.

The productoin method of anthranilic acid methyl ester:

Firstly, the o-formamide benzoic acid amine is generated through amidation reaction with phthalic anhydride and ammonia water as raw materials, then the sodium hydroxide solution is added directly and the sodium o-formamide benzoate is generated through displacement reaction, the ammonia in the reaction solution is removed, and then the methanol solution and the sodium hypochlorite solution are added to the reaction solution to form paste like anthranilic acid methyl ester. Then it will be heated and dissolved in water. Finally, the mixture of anthranilic acid methyl ester and water was distilled to obtain anthranilic acid methyl ester.