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Brief Introduction of Na Saccharin

Na saccharin, also known as o-sulfonylbenzoimide sodium, was developed in 1879. It is the first synthetic non nutritive sweetener. It is soluble in water, and its sweetness in dilute solution is 200-500 times that of sucrose. When the concentration is large, it has bitter taste. When heated in acid condition, the sweetness disappears, and the bitter o-sulfamoyl benzoic acid can be formed. Because of its low calorie, not absorbed by human body, and can be automatically discharged with defecation, it has been used as a substitute for sugar in patients with obesity, hyperlipidemia, diabetes and caries. In addition, it can also be used as brightening agent, blood circulation testing agent, penetrant, etc. for nickel chromium plating, with a wide range of uses.

Na saccharin usually contains two molecules of crystal water, which is colorless crystal. It is easy to be weathered and lose about half of crystal water to become white powder. The sweetness is 200-500 times of sucrose, generally 300 times, and the sweetness threshold is about 0.00048%. Soluble in water, slightly soluble in ethanol, the aqueous solution is slightly alkaline. Its thermal stability in aqueous solution is better than that in saccharin, and there is no change when heated at 100 ℃ for 2 hours. The sweetness of aqueous solution decreased slowly after long time storage. The molecular weight of anhydrous substance is 205.17, and the melting point is 226-231 ℃.

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